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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCQ
All Species:
17.88
Human Site:
S348
Identified Species:
26.22
UniProt:
Q04759
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04759
NP_006248.1
706
81865
S348
P
Q
G
I
S
W
E
S
P
L
D
E
V
D
K
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
S348
P
Q
G
I
S
W
E
S
P
L
D
E
V
D
K
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
D793
V
A
G
E
D
S
Q
D
N
S
G
T
Y
G
K
Dog
Lupus familis
XP_849292
706
81555
S348
P
Q
G
I
S
W
E
S
P
L
D
G
M
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q02111
707
81555
S348
P
Q
G
I
S
W
D
S
P
L
D
G
S
N
K
Rat
Rattus norvegicus
Q9WTQ0
707
81732
S348
P
Q
G
I
C
W
E
S
P
L
D
G
A
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
L350
P
Q
G
I
S
W
E
L
P
P
E
E
V
M
R
Chicken
Gallus gallus
NP_001006133
699
80179
G337
Q
Y
D
K
L
W
E
G
S
T
A
K
A
A
P
Frog
Xenopus laevis
Q7LZQ8
671
76506
A313
K
I
G
P
G
N
K
A
A
G
R
E
G
G
K
Zebra Danio
Brachydanio rerio
Q7SY24
670
76288
S317
G
P
S
K
T
D
G
S
S
S
N
A
I
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
K307
L
L
D
F
N
F
I
K
V
L
G
K
G
S
F
Honey Bee
Apis mellifera
XP_394743
624
71014
N303
K
Y
N
V
T
D
F
N
F
L
K
V
L
G
K
Nematode Worm
Caenorhab. elegans
P34722
704
80280
K350
Q
Y
S
V
E
E
Q
K
E
T
D
E
Y
M
D
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
I303
V
V
L
E
D
D
D
I
E
C
T
M
V
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
L720
S
G
E
I
Q
E
D
L
E
V
D
H
I
D
L
Red Bread Mold
Neurospora crassa
P87253
1142
127954
Q716
D
E
Y
S
A
Q
Q
Q
Q
G
Y
G
S
P
Q
Conservation
Percent
Protein Identity:
100
99.7
33.6
96.7
N.A.
94.7
94
N.A.
86.1
63.3
33.9
34.1
N.A.
42.9
43.2
47.1
47.8
Protein Similarity:
100
99.7
45.1
98.3
N.A.
97.5
96.8
N.A.
92.9
77.1
48.2
49.2
N.A.
58.7
58.9
64.1
62
P-Site Identity:
100
100
13.3
80
N.A.
73.3
80
N.A.
66.6
13.3
20
13.3
N.A.
6.6
13.3
13.3
6.6
P-Site Similarity:
100
100
20
93.3
N.A.
86.6
80
N.A.
80
20
33.3
33.3
N.A.
26.6
40
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.2
26.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.3
40.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
7
0
0
7
7
0
7
7
13
7
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
7
0
13
0
13
19
19
7
0
0
44
0
0
25
7
% D
% Glu:
0
7
7
13
7
13
38
0
19
0
7
32
0
13
0
% E
% Phe:
0
0
0
7
0
7
7
0
7
0
0
0
0
0
7
% F
% Gly:
7
7
50
0
7
0
7
7
0
13
13
25
13
19
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
7
0
44
0
0
7
7
0
0
0
0
13
0
0
% I
% Lys:
13
0
0
13
0
0
7
13
0
0
7
13
0
0
57
% K
% Leu:
7
7
7
0
7
0
0
13
0
44
0
0
7
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
7
13
0
% M
% Asn:
0
0
7
0
7
7
0
7
7
0
7
0
0
7
0
% N
% Pro:
38
7
0
7
0
0
0
0
38
7
0
0
0
7
7
% P
% Gln:
13
38
0
0
7
7
19
7
7
0
0
0
0
0
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
13
% R
% Ser:
7
0
13
7
32
7
0
38
13
13
0
0
13
13
0
% S
% Thr:
0
0
0
0
13
0
0
0
0
13
7
7
0
0
0
% T
% Val:
13
7
0
13
0
0
0
0
7
7
0
7
25
0
0
% V
% Trp:
0
0
0
0
0
44
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
19
7
0
0
0
0
0
0
0
7
0
13
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _